Articles since 2002

(most of them online, please click the link to download them)

115. Dumortier M, Perez-Martin A, Pierrisnard E, Mercier J, Brun JF. Regular exercise (3x45 min/wk) decreases plasma viscosity in sedentary obese, insulin resistant patients parallel to an improvement in fitness and a shift in substrate oxidation balance. Clin Hemorheol Microcirc. 2002;26(4):219-29.

116. J.F. Brun, H. Belhabas, M. CH. Granat, C. Sagnes, G. Thöni, J.P. Micallef and J. Mercier . Postexercise red cell aggregation is negatively correlated with blood lactate rate of disappearance.  Clin Hemorheol Microcirc. 2002;26(4):231-9.

117. J Manetta, A Perez-Martin, J F Brun, A Callis, C Préfaut, J Mercier: Fuel oxidation during exercise in middle-aged men: effect of training and glucose disposal. Med Sci Sports Exerc 2002 Mar;34(3):423-9.

118. J Manetta, JF Brun, L Maimoun, O Galy, O Coste, JL Raibaut, J Mercier. Carbohydrate dependence during hard-intensity exercise in trained cyclists in the competitive season: importance of training status. Int J Sports Med. 2002 Oct;23(7):516-23

119. Brun JF, Tikhomirova I, Roitman EV, Muravyov A. Highlights of the 3rd Yaroslavl International Congress on Hemorheology, 29-31 July 2001, Yaroslavl, Russia. Clin Hemorheol Microcirc. 2002;27(1):43-56.

120: Rabhi YA, Fabbro-Peray P, Dauzat M, Montesinos P, Oliva-Lauraire MC, Lopez FM, Quere I, Gris JC, Brun JF, Pourcelot L. Towards a quantitative in vivo evaluation of venous blood echogenicity: image processing versus subjective assessment.Clin Hemorheol Microcirc. 2002;27(1):27-41.

121: Gaudard A, Varlet-Marie E, Monnier JF, Janbon C, Quere I, Bressolle F, Brun JF. Exercise-induced central retinal vein thrombosis: Possible involvement of hemorheological disturbances. A case report.Clin Hemorheol Microcirc. 2002;27(2):115-122.

122: Brun JF. Hormones, metabolism and body composition as major determinants of blood rheology: Potential pathophysiological meaning. Clin Hemorheol Microcirc. 2002;26(2):63-79.

123: Aissa Benhaddad A, Monnier JF, Fedou C, Micallef JP, Brun JF. Insulin-like growth factor-binding protein 1 and blood rheology in athletes. Clin Hemorheol Microcirc. 2002;26(3):209-17.

124: Brun JF. Exercise hemorheology as a three acts play with metabolic actors: Is it of clinical relevance? Clin Hemorheol Microcirc. 2002;26(3):155-74. (or preprint)

125: Perez-Martin A, Raynaud E, Hentgen C, Bringer J, Mercier J, Brun JF. Simplified measurement of insulin sensitivity with the minimal model procedure in type 2 diabetic patients without measurement of insulinemia. Horm Metab Res. 2002 Feb;34(2):102-6.

126. Peyreigne C, Raynaud E, Fedou C, Prefaut C, Brun JF, Mercier J. Does Growth Hormone Treatment Alter Skeletal Muscle Mitochondrial Respiration in Rats? Horm Res. 2002;58(6):287-291

127. I Aloulou, JF Brun, et J Mercier. Le coût glucidique du watt : une constante biologique ? Sci Sports 2002, 17, 315-317

128. Thöni G, C Fédou, Brun JF, J Fabre, E Renard, J Reynes, A Varray, J Mercier. Reduction of fat accumulation and lipid disorders by individualized light aerobioc training in human immunodeficiency virus infected patients with lipodystrophy and/or dyslipidemia. Diabetes Metab 2002, 28, 397-404

129. Manetta J, Brun JF, Maimoun L, Callis A, Préfaut C, Mercier J.  Effect of training on the growth hormone - IGF-I axis during exercise in middle-aged men. Relationship to glucose homeostasis. Am J Physiol (Endocrinol Metab) 283, E929-936, 2002

130. A Gaudard, E Varlet-Marie, F Bressolle, J Mercier, JF Brun. Hemorheological correlates of fitness and unfitness in athletes: moving beyond the apparent "paradox of hematocrit"? Clin Hemorheol Microcirc. 2003;28(3):161-73.

131. E. Varlet-Marie, A. Gaudard, J Mercier, F. Bressolle and J-F. Brun. Is the feeling of heavy legs in overtrained athletes related to impaired hemorheology? Clin Hemorheol Microcirc. 2003;28(3):151-9.

132. E. Varlet-Marie, A. Gaudard, J-F. Monnier, J-P. Micallef, J. Mercier, F. Bressolle and J-F. Brun Reduction of red blood cell disaggregability during submaximal exercise : relationship with fibrinogen levels. Clin Hemorheol Microcirc. 2003;28(3):139-149.

133. Varlet-Marie E, Gaudard A, Mercier J, Bressolle F, Brun JF. Is whole body impedance a predictor of blood viscosity? Clin Hemorheol Microcirc. 2003;28(3):129-137.

134.A Gaudard, E Varlet-Marie, F Bressolle, J Mercier, J-F Brun. Nutrition as a determinant of blood rheology and fibrinogen in athletes. Clin Hemorheol Microcirc. 2004;30(1):1-8.

135. Brandou F , Dumortier M, Garandeau P, Mercier J and Brun JF. Effects of a two-months rehabilitation program on substrate utilization during exercise in obese adolescents. Diabetes Metab 2003, 29, 20-7

136. Lautier C, El Mkadem SA, Renard E, Brun JF, Gris JC, Bringer J, Grigorescu  Complex haplotypes of IRS2 gene are associated with severe obesity and  reveal heterogeneity in the effect of Gly1057Asp mutation. Hum Genet 2003 Apr 10

137. J Manetta, JF Brun, L Maimoun, C Fédou, C Préfaut JL Raibaut, J Mercier. The effects of intensive training on Insulin like growth factor I (IGF-I) and IGF binding proteins 1 and 3 in competitive cyclists: relationships with glucose disposal.  J Sports Sci. 2003 Mar;21(3):147-54. 

138. Dumortier M, Brandou F, Pérez-Martin A, Fédou C, Mercier J, Brun JF. Low intensity endurance exercise targeted for lipid oxidation improves body composition and insulin sensitivity in patients with the metabolic syndrome.Diabetes Metab 2003 Nov;29(5):509-18.

139. Manetta J, Brun JF, Fedou C, Maimoun L, Prefaut C, Mercier J. Serum levels of insulin-like growth factor - I (IGF-I) and IGF- binding proteins -1 and -3 in middle age and young athletes versus sedentary men: relationships with glucose disposal. Metabolism 2003, 52, 821-826

140. Connes P,Bouix D, Durand F, Kippelen P, Mercier J, Prefaut C, Brun JF and Caillaud C : Is hemoglobin desaturation related to blood viscosity in athletes during exercise? Int J Sports Med. 2004 Nov;25(8):569-74. 

141. J. -F. Brun, A. Monroche et les Membres du groupe Surentraînement de la Société française de médecine du sport . Editorial. Le surentraînement. Science & Sports 2003, 18, 281

142. J. -F. Brun.Le surentraînement : à la recherche d'un outil d'évaluation standardisé utilisable en routine Science & Sports 2003, 18,  282-286

143. I. Aloulou, J. Manetta, M. Dumortier, F. Brandou, E. Varlet-Marie, C. Fédou, J. Mercier and J. -F. Brun . Effets en miroir de l'entraînement et du surentraînement sur la fonction somatotrope et la balance glucidolipidique à l'exercice Science & Sports 2003, 18,  305-307  

144. J. -F. Brun, A. Gaudard, E. Varlet-Marie and J. Mercier  L'hémorhéologie permet-elle de comprendre le " paradoxe de l'hématocrite " lors de l'entraînement et du surentraînement ? = Does hemorheology explain the paradox of hematocrit in training and overtraining?,Science & Sports 2003, 18,  308-311  

145. E. Varlet-Marie, J. Mercier and J. -F. Brun Le " syndrome des jambes lourdes " chez les athlètes surentraînés est-il le reflet de désordres hémorhéologiques ? Science & Sports 2003, 18,  312-314 

146. E. Varlet-Marie  and J. -F. Brun. Generalized predictive equation by biological impedancemetry.  Clin Hemorheol Microcirc 2003 2004;30(3-4):471-5

147. E. Varlet-Marie  and J. -F. Brun. Extension  of equations for predicting viscosity parameters with whole body bioelectrical impedance to a sedentary population.  Clin Hemorheol Microcirc2004;30(3-4):393-8

148. J.F. Brun I Aloulou and E. Varlet-Marie. Hemorheological aspects of the metabolic syndrome : Markers of insulin resistance, obesity or hyperinsulinemia. Clin Hemorheol Microcirc 2004;30(3-4):203-9.

149. E. Varlet-Marie and J.F. Brun.Hemorheological disturbances in the overtraining syndrome.  Clin Hemorheol Microcirc. 2004;30(3-4):211-8 

150. E Varlet-Marie and J F Brun. Reciprocal relationships between blood lactate and hemorheology in athletes: another hemorheologic paradox?.Clin Hemorheol Microcirc 2004;30(3-4):331-7 

151. J F Brun , E Varlet-Marie, D. Cassan, J Manetta, and J Mercier. Blood fluidity is related to the ability to oxidize lipids at exercise.Clin Hemorheol Microcirc 2004;30(3-4):339-43. 

152. J F Brun , Aloulou I, E Varlet-Marie Type 2 diabetics with higher plasma viscosity exhibit a higher blood pressure. Clin Hemorheol Microcirc. 2004;30(3-4):365-72.

153. Connes Ph, Bouix D, Py G, Caillaud C, Kippelen P Brun JF, Varray A, Prefaut C, Mercier J .Does exercise-induced hypoxemia modify lactate influx into erythrocytes and hemorheological parameters in athletes ? J Appl Physiol.2004; 97: 1053-1058

154. Chevassus H, Mourand I, Molinier N, Lacarelle B, Brun JF, Petit P. Assessment of single-dose benzodiazepines on insulin secretion, insulin sensitivity and glucose effectiveness in healthy volunteers: a double-blind, placebo-controlled, randomized cross-over trial. BMC Clin Pharmacol. 2004 Mar 4;4(1):3. Epub 2004 Mar 04.    (or: html)

155. Connes P, Bouix D, Py G, Préfaut C, Mercier J, Brun JF, Caillaud C. Opposite effects of in vitro lactate on erythrocyte deformability in athletes and untrained subjects. (Clin Hemorheol Microcirc, 2004;31(4):311-8)

156. Brandou F, Brun JF, Mercier J. Limited accuracy of surrogates of insulin resistance during puberty in obese and lean children at risk for altered glucoregulation. J. Clin. Endocrinol. Metab., Feb 2005; 90: 761 - 767; see also the Comment in: J Clin Endocrinol Metab. 2005 Jul;90(7):4418-9; author reply  p 4419

157. Manetta J.; Brun, J.F.; Prefaut, C.; Mercier,.J. Substrate oxidation during exercise at moderate and hard intensity in middle-aged and young athletes versus sedentary men  Metabolism 2005, 54 (11): 1411-1419

158.Maso F, Lac G, Brun JF, et le groupe de Consensus (G Bernardié, X Bigard, V Bricout, F Brue, F Depiesse, A Favre-Juvin, J Giordan, F Limas, N Paruit, P. Rochcongar, V. Rousseaux-Blanchi, B Serrurier). Le questionnaire de détection des signes précoces de surentraînement : étude multicentrique. Science & Sports, 2005, 20, 12-20

159. Dumortier M, Thöni G, Brun JF, Mercier J . Substrate oxidation during exercise: impact of time interval from the last meal in obese women.  Dumortier. Int J Obes Relat Metab Disord. 2005 Aug;29(8):966-74.

160.  Metz L, Sirvent P, Py G, Brun JF, Fedou C, Raynaud E, Mercier J. Relationship between blood lactate concentration and substrate utilization during exercise in type 2 diabetic postmenopausal women. Metabolism. 2005 Aug 54(8):1102-7.

161. A. Favre-Juvin and et les membres du groupe surentraînement de la SFMS (X Bigard, JF Brun, V Bricout, JL Chatard, P Flore, M Guinot, N Koulman, G Lac, M Rousseau-Blanchi, B Serrurier).  Le surentraînement : place de l'interrogatoire dans le diagnostic . Science & Sports 20, 5-6, 314-316

 162. Brandou F, Savy-Pacaux AM, Marie J, Bauloz M, Maret-Fleuret I, Borrocoso S, Mercier J, Brun JF. Impact of high- and low-intensity targeted exercise training on substrate utilization in obese boys submitted to a hypocaloric diet. Diabetes Metab 2005, 31, 327-335

163. F. Brandou, A.M. Savy-Pacaux, J. Marie, J.F. Brun, J. Mercier. Comparison of the type of substrate oxidation during exercise between pre and post pubertal markedly obese boys. Int J Sports Med (definitely accepted)

164. I. Aloulou, J. F. Brun and J. Mercier. Evaluation of insulin sensitivity and glucose effectiveness during a standardized breakfast test: comparison with the minimal model analysis of an intravenous glucose tolerance test. Metabolism, 2006, 55 (N°5): 676-90

165. C Fayolle, JF Brun, MD, J Bringer,  J Mercier, E Renard.Accuracy of Continuous Subcutaneous Glucose Monitoring with the GlucoDay in Type 1 Diabetic Patients Treated by Subcutaneous Insulin Infusion during Exercise of Low and High Intensity. Diabetes and Metabolism 2006, 32, 313-320

166. I Aloulou, E Varlet-Marie, J Mercier and J-F Brun. The hemorheological aspects of the metabolic syndrome are a combination of separate effects of insulin resistance, hyperinsulinemia and adiposity Clin Hemorheol Microcirc 2006;35, 113-119 

167. I Aloulou, E Varlet-Marie, J Mercier and J-F Brun. Hemorheological disturbances correlate with the lipid profile but not with the NCEP-ATPIII score of the metabolic syndrome. Clin Hemorheol Microcirc 2006;35, 207-212 

168. J Manetta, I Aloulou, E Varlet-Marie, J Mercier and J-F Brun. Partially opposite hemorheological effects of aging and training at middle age. Clin Hemorheol Microcirc 2006;35, 239-244 

169.  E Varlet-Marie, J. Mercier and JF Brun. Is plasma viscosity a predictor of overtraining in athletes ? Clin Hemorheol Microcirc 2006;35, 329-332

170. I Aloulou, E Varlet-Marie, J Mercier and JF. Brun. Hemorheologic effects of low intensity endurance training in sedentary patients suffering from the metabolic syndrome. Clin Hemorheol Microcirc 2006;35, 333-339

171. Brandou F, Aloulou I., Razimbaud A., Fédou C., Mercier J., Brun J.F. Lower ability to oxidize lipids in Adult Growth Hormone Deficiency patients. Reversal under Growth Hormone treatment. Clin Endocrinol (Oxford) 2006, 65, 423-428

173. Connes P, Yalcin O, Baskurt O, Brun JF, Hardeman M. In health and in a normoxic environment, VO2 max is/is not limited primarily by cardiac output and locomotor muscle blood flow.1: J Appl Physiol. 2006 Jun;100(6):2099. 

174. E. Ghanassia, J.F. Brun, C. Fedou, E. Raynaud, J. Mercier: Substrate oxidation during exercise : Type 2 Diabetes is associated with a decrease in lipid oxidation and an earlier shift towards carbohydrate utilization. Diabetes Metab 2006, 32, 604-610 

175. Bricout V; Guinot M ; Duclos M ; Koulmann N ; Serrurier B; Brun JF; Flore P; Chatard JC; Bigard X; Favre Juvin A. .Apports des examens biologiques dans le diagnostic du surentrainement. Science et Sports, 2006, 21, 319-350

176. E. Ghanassia, J.F. Brun,  J. Mercier, E. Raynaud: Critical review : oxidative mechanism at rest and during exercise. Clin Chem Acta 2007, 383, 1-20

177 JF Brun, E Jean, E Ghanassia, S Flavier, J Mercier Réentraînement des maladies métaboliques ciblé individuellement par la calorimétrie d'effort. Ann Réaadapt Med Phys 2007 2007 Jul;50(6):520-527

178 JF Brun, E Jean, E Ghanassia, S Flavier, J Mercier  Metabolic training: proposals for new paradigms of exercise training in metabolic diseases using individual targetting with exercise calorimetry Ann Readapt Med Phys. 2007 Jul;50(6):528-534

179 Connes P, Caillaud C, Py G, Mercier J, Hue O, Brun JF.Maximal exercise and lactate do not change red blood cell aggregation in well trained athletes. Clin Hemorheol Microcirc. 2007;36(4):319-26.

180. Bordenave S, Flavier S, Fedou C, Brun JF, Mercier J.  Exercise calorimetry in sedentary patients: procedures based on short 3 min steps underestimate carbohydrate oxidation and overestimate lipid oxidation. Diabetes Metab. 2007 Nov;33(5):379-84  

181. Flavier S, Rolland MO, Eude M, Fedou C, Brun JF, Maire I, Mercier J, Raynaud E. Late diagnosis of a McArdle disease's case (type V glycogenosis). Ann Biol Clin (Paris). 2007 Oct 4;65(5):550-554.  

182. JF Brun, Ph Connes, and E Varlet-Marie. Alterations of blood rheology during and after exercise are both consequences and modifiers of body's adaptation to muscular activity. Science & Sports, Volume 22, Issue 6, December 2007, Pages 251-266

183. Brun JF, Bordenave S, Mercier J, Jaussent A, Picot MC, Préfaut C. Cost-sparing effect of twice-weekly targeted endurance training in type 2 diabetics: A one-year controlled randomized trial. Diabetes Metab. 2008 Jun;34(3):258-65.

184. Bordenave S, Brandou F, Manetta J, Fédou C, Mercier J, Brun JF. Effects of acute exercise on insulin sensitivity, glucose effectiveness and disposition index in type 2 diabetic patients. Diabetes Metab. 2008 Jun;34(3):250-7.

185. Bordenave S, Metz L, Flavier S, Lambert K, Ghanassia E, Dupuy AM, Michel F, Puech-Cathala AM, Raynaud E, Brun JF, Mercier J. Training-induced improvement in lipid oxidation in type 2 diabetes mellitus is related to alterations in muscle mitochondrial activity. Effect of endurance training in type 2 diabetes. Diabetes Metab. 2008 Apr;34(2):162-168.

186. C. Fédou, J. Fabre, V. Baillat, J. Reynes, J.F. Brun, J. Mercier . Balance des substrats à l'exercice chez des patients infectés par le VIH 1 et présentant un syndrome lipodystrophique : Effet d'un réentraînement ciblé par la calorimétrie d'effort . Science & Sports 2008, 23: 189-192 

188. J.-F. Brun, S. Bordenave, E. Ghanassia, M.-C. Picot, A. Jaussent, J. Mercier, C. Prefaut Le réentraînement à l'activité physique dans le diabète de type 2 réduit les dépenses de santé : résultats d'une étude prospective. Science & Sports 2008, 23: 193-197

188 J.-F. Brun, C. Fédou, E. Grubka, M. Karafiat, E. Varlet-Marie, J. Mercier Moindre utilisation des lipides à l'exercice chez le diabétique de type 1. Science & Sports 2008, 23: 198-200  

189. J.-F. Brun, J.-M. Pégot, J. Mercier Overtraining syndrome : la piste de la suractivité ? Science & Sports 2008, 23: 310-312

190 JF Brun, M Traverso, C Fédou, E Renard, J Mercier. Deux mythes concernant l'exercice chez le diabétique de type 1: le seuil hyperglycémique de 2, 5 g/l de contre-indication à l'effort et le " glucose pulse ". (Reassessing two myths about exercise in type 1 diabetics: the hyperglycemic threshold at 250 mg/dL counterindicating exercise, and the " glucose pulse ".). Science et Sports, 2009, 24, 108-110

191 A.-J. Romain, J. Attal, A. Hermès, D. Capdevielle, R. Raimondi, J.-P. Boulenger and J.-F. Brun. Effets d’un réentraînement en endurance au LIPOXmax chez des patients psychiatriques traités par psychotropes (Effects of endurance training targetd at the LIPOXmax in psychiatric patients treated by neuroleptics) Science & Sports Volume 24, Issue 5, November 2009, Pages 265-268

192  E. Varlet-Marie, E. Grubka, M. Karafiat, C. Fédou, E. Raynaud de Mauverger, J.-F. Brun Comparaison de plusieurs formules de calcul de la masse maigre par bio-impédancemétrie avec l'absorptiométrie biphotonique (Dexa) Science & Sports, Volume 24, Issues 3-4, June-August 2009, Pages 202-206

193  J.-F. Brun, C. Boegner, E. Raynaud, J. Mercier Contrairement à une idée reçue, les femmes n'oxydent pas plus de lipides à l'effort que les hommes, mais leur Lipoxmax survient à une puissance plus élevée . Science & Sports, Volume 24, Issue 1, February 2009, Pages 45-48

194  J.-F. Brun, E. Varlet-Marie, C. Faugoin, J. Mercier Présentation clinique, biologique et ergométrique de six cas d'overtraining syndrome Science & Sports, Volume 24, Issue 1, February 2009, Pages 40-44

A.-J. Romain, J. Attal, A. Hermès, D. Capdevielle, R. Raimondi, J.-P. Boulenger, J.-F. Brun. Effets d'un réentraînement en endurance au LIPOXmax chez des patients psychiatriques traités par psychotropes Science & Sports, Volume 24, Issue 5, November 2009, Pages 265-268 

E. Varlet-Marie, E. Grubka, M. Karafiat, C. Fédou, E. Raynaud de Mauverger, J.-F. Brun. Comparaison de plusieurs formules de calcul de la masse maigre par bio-impédancemétrie avec l'absorptiométrie biphotonique (Dexa). Science & Sports, Volume 24, Issues 3-4, June-August 2009, Pages 202-206

195. Attaoua R, Ait El Mkadem S, Lautier C, Kaouache S, Renard E, Brun JF, Fedou C, Gris JC, Bringer J, Grigorescu F. Association of the FTO gene with obesity and the metabolic syndrome is independent of the IRS-2 gene in the female population of Southern France. Diabetes Metab. 2009 Dec;35(6):476-83.

J.-F. Brun, E. Varlet-Marie, C. Faugoin, J. Mercier. Présentation clinique, biologique et ergométrique de six cas d'overtraining syndrome. Science & Sports, Volume 24, Issue 1, February 2009, Pages 40-44 

196. Connes P, Frank S, Martin C, Shin S, Aufradet E, Sunoo S, Klara B, Raynaud de Mauverger E, Romana M, Messonnier L, Kang J, Varlet-Marie E, Feasson L, Hardy-Dessources MD, Wilhelm B, Brun JF. New fundamental and applied mechanisms in exercise hemorheology. Clin Hemorheol Microcirc. 2010;45(2-4):131-41.

197. Aguer C, Mercier J, Yong Wai Man C, Metz L, Bordenave S, Lambert K, Jean E, Lantier L, Bounoua L, Brun JF, Raynaud de Mauverger E, Andreelli F, Foretz M, Kitzmann . M. Intramyocellular lipid accumulation is associated with permanent relocation ex vivo and in vitro of fatty acid translocase (FAT)/CD36 in obese patients. Diabetologia. 2010, 53, 1151-1163

198. E Varlet-Marie, I Aloulou, J Mercier JF Brun. Prediction of hematocrit and red cell deformability with whole body biological impedance. Clin Hemorheol Microcirc 2010, 44, N° 4, 237-244 

199. JF Brun, E Varlet-Marie, Ph Connes and I Aloulou. Hemorheological alterations related to training and overtraining. Biorheology 2010, 47, N° 2, 95-115      (uncorrected proofs)

200. E. Ghanassia, J.F. Brun, C. Fédou, J. Mercier, and E. Raynaud de Mauverger, Limited predictive value of the International Diabetes Federation definition of the Metabolic Syndrome for the diagnosis of Insulin Resistance measured with the Oral Minimal Model. Ann. Biol. Clin. 67(2009),535-42. other link here

201. Brun JF, Ghanassia E, Fédou C, Bordenave S, Raynaud de Mauverger E, Mercier J. Assessment of insulin sensitivity (SI) and glucose effectiveness (SG) from a standardized hyperglucidic breakfast test in type 2 diabetics exhibiting various levels of insulin resistance. Acta Diabetol. 2013 Apr;50(2):143-53.

202. JF Brun, E Varlet-Marie, I Aloulou, M Sardinoux, E Raynaud de Mauverger and J Mercier: Insulin resistance as a hemorheologic disease. Series on Biomechanics: Vol 25, No 1-2 (2010), 83-90

202b. B. Marson, J.-F. Brun, J.-P. Cristol, M. Audran, J. Mercier, E. Varlet-Marie  o Étude de l'effet de la rHuEpo sur le stress oxydant à l'exerciceScience & Sports, Volume 25, Issue 2, April 2010, Pages 68-73

203. JF Brun, E Varlet-Marie and J Mercier. Whole body bioimpedance as a mirror of the influence of hemorheological factors on electric properties of blood: a step forward with Hanai's mixture conductivity theory. Series on Biomechanics: Vol 25, No 1-2 (2010), 100-104

Connes P, Frank S, Martin C, Shin S, Aufradet E, Sunoo S, Klara B, Raynaud de Mauverger E, Romana M, Messonnier L, Kang J, Varlet-Marie E, Feasson L, Hardy-Dessources MD, Wilhelm B, Brun JF. New fundamental and applied mechanisms in exercise hemorheology. Clin Hemorheol Microcirc. 2010;45(2-4):131-41. 

J.-F. Brun, P. Connes, E. Varlet-Marie. Alterations of blood rheology during and after exercise are both consequences and modifiers of body's adaptation to muscular activity. Science & Sports, Volume 22, Issue 6, December 2007, Pages 251-266 

204. G. Ninot , G. Moullec, M.C. Picot, A. Jaussent, M. Hayot, M. Desplan , J.F. Brun, J. Mercier , C. Prefaut.  Cost-saving effect of supervised exercise associated to COPD self-management education program. Respir Med. 2011 Mar;105(3):377-85. 

205. E Varlet-Marie and JF Brun. Prediction of RBC aggregability and deformability by whole body bioimpedance measurements analyzed according to Hanai's mixture conductivity theory. Clin Hemorheol Microcirc. 2011 Jan 1;47(2):151-61.

206 Ramos SB, Brun JF, Gray B, Rogerson S, Weatherby RP, Tajouri L, Marshall-Gradisnik SM. The effects of short term recombinant human growth hormone (rhGH) on blood rheology in healthy young males. Clin Hemorheol Microcirc. 2011 Jan 1;47(2):121-9.

207. P. Lavault, S. Deaux, A.-J. Romain, C. Fédou, J. Mercier, J.-F. Brun. Intérêt de la quantification de la masse musculaire pour interpréter la calorimétrie d’effort  Science & Sports 2011, 26 N°2:,88-91

 

208. J. Maurie, J.-F. Brun, E. Jean, A.-J. Romain, J. Mercier Comparaison de deux modalités différentes d’activité physique (SWEET et Lipoxmax) chez des diabétiques de type 2  Science & Sports 2011, 26 N°2:, 92-96

 

209. J.-F. Brun, C. Halbeher, C. Fédou, J. Mercier Quelles sont les limites de normalité du LIPOXmax ? Peut-on le prédire sans effectuer de calorimétrie d’effort ?  Science & Sports 2011, 26 N°3 Juin 2011 pp 166-169

 

210. J.-F. Brun, A.-J. Romain, J. Mercier Maximal lipid oxidation during exercise (Lipoxmax): From physiological measurements to clinical applications. Facts and uncertainties Science & Sports 2011, 26 N°2: 57-71

211. Brun JF, Varlet-Marie E, Raynaud de Mauverger E, Mercier J. Minimal model-derived insulin sensitivity, insulin secretion and glucose tolerance: relationships with blood rheology. Clin Hemorheol Microcirc. 2012;51(1):21-7.

212. Brun JF, Varlet-Marie E, Raynaud de Mauverger E, Mercier J. Both overall adiposity and abdominal adiposity increase blood viscosity by separate mechanisms. Clin Hemorheol Microcirc. 2011;48(4):257-63.

213. Brun JF, Varlet-Marie E, Romain AJ, Raynaud de Mauverger E. Interrelationships among body composition, blood rheology and exercise performance. Clin Hemorheol Microcirc. 2011;49(1-4):183-97.

214. J.-F. Brun, C. Fédou, J. Mercier Exploration détaillée des composantes de la glycorégulation chez des sportifs sujets aux hypoglycémies d’effort. Intérêt de l’oral minimal model  (Detailed exploration of the components of glucose metabolism in athletes prone to exercise hypoglycaemia. Interest of the oral minimal model) Science & Sports 2011, Vol 26 - N° 5, pp 286-291 

215. J.F. Brun, E. Varlet-Marie, I. Aloulou, E. Raynaud de Mauverger Relationships between insulin sensitivity measured with the oral minimal model and blood rheology Clin Hemorheol Microcirc. 2012;51(1):29-34

216. Romain AJ, Brun JF, Varlet-Marie E, Raynaud de Mauverger E. Effects of exercise training on blood rheology : a meta-analysis. Clin Hemorheol Microcirc. 2011;49(1-4):199-205

217. Varlet-Marie E, Brun JF, Fédou C, Raynaud de Mauverger E. Blood rheology and body composition as determinants of exercise performance in male soccer players. Clin Hemorheol Microcirc. 2011;49(1-4):225-30.

218.  Brun JF, Varlet-Marie E, Cassan D, Raynaud de Mauverger E. Blood rheology and body composition as determinants of exercise performance in female rugby players. Clin Hemorheol Microcirc. 2011;49(1-4):207-14.

219. Brun JF, Varlet-Marie E, Fédou C, Raynaud de Mauverger E. Body composition and exercise performance as determinants of blood rheology in middle-aged patients exhibiting the metabolic syndrome. Clin Hemorheol Microcirc. 2011;49(1-4):215-23.

219. E Makni, W Moalla, Y Trabelsi, G Lac, JF Brun, Z Tabka and M Elloumi. Six-minute walking test predicts maximal fat oxidation in obese children. Int J Obes (Lond). 2012 Jul;36(7):908-13.

220. Desplan M., Pillard F., Brun JF, Prefaut C., Dauvilliers Y., Mercier J., Avignon A. Decreased fat oxydation rate during exercise in severe obstructive apnea syndrome. Diabetes and Metabolism, vol. 38, no. 3, pp. 236–242, 2012

221. Gmada N, Marzouki H, Haboubi M, Tabka Z, Shephard RJ, Bouhlel E. Crossover and maximal fat-oxidation points in sedentary healthy subjects: methodological issues. Diabetes Metab. 2012 Feb;38(1):40-5. 

222. J.-F. Brun, B. Marti, C. Fédou, A. Farré, E. Renard, J. Place, J. Mercier  La baisse de la glycémie à l’exercice en plateau chez le diabétique insuliné est déterminée par la glycémie de départ et l’insulinémie Science & Sports, Volume 27, 2012, Issue 2, Pages 111-114 

223. Brun JF, Malatesta D, Sartorio A. .Maximal lipid oxidation during exercise: A target for individualizing endurance training in obesity and diabetes? J Endocrinol Invest. 2012 Jul;35(7):686-91

224. AJ Romain, M. Carayol, M Desplan, C Fédou, G Ninot, J Mercier, A Avignon, JF Brun. Physical activity targeted at maximal lipid oxidation: a meta-analysis. J Nutr Metab. 2012;2012:285395 

225. Connes P, Simmonds MJ, Brun JF, Baskurt OK. Exercise hemorheology: Classical data, recent findings and unresolved issues. Clin Hemorheol Microcirc. 2013;53(1-2):187-99..

226. Brun JF, Varlet-Marie E, Romain AJ, Guiraudou M, Raynaud de Mauverger E.. Exercise hemorheology: moving from old simplistic paradigms to a more complex picture. Clin Hemorheol Microcirc. 2013 Jan 1;55(1):15-27 (IF = 3.40).

227. Varlet-Marie E, Guiraudou M, Fédou C, Raynaud de Mauverger E, Durand F, Brun JF. Nutritional and metabolic determinants of blood rheology differ between trained and sedentary individuals. Clin Hemorheol Microcirc. 2013 Jan 1;55(1):39-54. (IF = 3.40).

228. Guiraudou M, Varlet-Marie E, Raynaud de Mauverger E, Brun JF. Obesity-related increase in whole blood viscosity includes different profiles according to fat localization.  Clin Hemorheol Microcirc. 2013 Jan 1;55(1):63-73.. (IF = 3.40).

229. J.-F. Brun, M. Guiraudou, C. Mardemootoo, A. Traoré, I. Raingeard, A. Chalançon, A. AvignonValidation de la mesure segmentaire de la composition corporelle en comparaison avec la DEXA : intérêt de la mesure de la masse grasse tronculaire. Science & Sports (2013) 28, 158-162

230. Hokayem M, Blond E, Vidal H, Lambert K, Meugnier E, Feillet-Coudray C, Coudray C, Pesenti S, Luyton C, Lambert-Porcheron S, Sauvinet V, Fedou C, Brun JF, Rieusset J, Bisbal C, Sultan A, Mercier J, Goudable J, Dupuy AM, Cristol JP, Laville M, Avignon A.Grape Polyphenols Prevent Fructose-Induced Oxidative Stress and Insulin Resistance in first-degree relatives of Type 2 Diabetic Patients. Diabetes Care, . 2013 Jun;36(6):1454-61.

231. Radermecker RP, Fayolle C, Brun JF, Bringer J, Renard E. Accuracy assessment of online glucose monitoring by a subcutaneous enzymatic glucose sensor during exercise in patients with type 1 diabetes treated by continuous subcutaneous insulin infusion. Diabetes Metab. 2013 May;39(3):258-62.

232. N. Gmada, H. Marzouki, R. Haj Sassi, Z. Tabka, R. Shephard, J.-F. Brun, E. Bouhlel: Relative and absolute reliability of the crossover and maximum fat oxidation points and their relationship to ventilatory threshold Original Research Article Science & Sports, Science & Sports, Volume 28, Issue 4, September 2013, Pages e99-e105 

 

233. M. Pollatz, M. Guiraudou, A.-J. Romain, C. Fédou, J.-F. Brun, J. Mercier. Les effets d’un réentraînement de 45 minutes au LIPOXmax sur le comportement alimentaire de patients obèses sont analogues le matin et l’après-midi. Science & Sports, 2014, 29: 57-61

 

234. J.-F. Brun, A.-J. Romain, M. Guiraudou, Ch. Fédou, J. Mercier. Stability over time of the level of maximal lipid oxidation during exercise (Stabilité dans le temps du niveau maximal d’oxydation des lipides à l’exercice) Science & Sports, Volume 29, Issue 3, June 2014, Pages 168-171 

 

235. J.F. Brun, C. Roubille, A. Le Quellec, J. Mercier Une nouvelle observation d'intolérance à l'effort avec hypokaliémie chez un porteur sain de la mucoviscidose Science & Sports, Volume 29, Issue 1, February 2014, Pages 46-50

236. J.-F. Brun, C. Boegner, C. Fédou. Hyperthyroïdie chez un sportif : aux frontières du surentraînement Science & Sports (accepté, sous presse) Science & Sports, Volume 29, Issue 2, April 2014, Pages 95-100

237. Brun JF, Varlet-Marie E, Chevance G, Pollatz M, Fedou C, Raynaud de Mauverger E: Versatility of 'hemorheologic fitness' according to exercise intensity: emphasis on the "healthy primitive lifestyle". Korea-Aust Rheol J 2014, 26 N°2 : 1-5

 

238.  Brun JF, Varlet-Marie E, Fedou C, Raynaud de Mauverger E. Are metabolically healthy obese patients also hemorheologically healthy? Clin Hemorheol Microcirc. 2015;61(1):39-46

240. Varlet-Marie E, Raynaud de Mauverger E, Brun JF: Are overall adiposity and abdominal adiposity separate or redundant determinants of blood viscosity? Clin Hemorheol Microcirc. 2015;61(1):31-8.

241. Besnier, F., Lenclume, V., Gérardin, P., Fianu, A., Martinez, J., Naty, N., Porcherat, S., Boussaid, K., Schneebeli, S., Jarlet, E., Hatia, S., Dalleau, G., Verkindt, C., Brun, J.F., Gonthier, M.P., Favier, F., 2015. Individualized exercise training at maximal fat oxidation combined with fruit and vegetable-rich diet in overweight or obese women: The LIPOXmax-Réunion randomized controlled trial. PLoS One 10, e0139246.

242. M. Guiraudou, L. Maimoun, J.-M. Dumas, M. Julia, I. Raingeard, J.-F. Brun. Composition corporelle mesurée par impédancemétrie segmentaire (BIAS) et performance de sprint chez les rugbymen. / Body composition measured by bioimpedance segmental (BIAS) analysis and sprint performance in rugby players. Science & Sports 2015, 30 [N°5] : pages 298-302

243. M. Guiraudou, C. Fédou, A.-J. Romain, A. Sferlazza, E. Calas, J.-F. Brun. Brief note: Effects over one year of low-intensity endurance exercise targeted at the level of maximal lipid oxidation. / Effets à un an de l'activité physique ciblée au LIPOXmax dans l'obésité Science & Sports 2015, 30 [N°5] : page e127-e131

244. Brun JF.Exercise Makes More than an Energy Deficit: Toward Improved Protocols for the Management of Obesity?  EBioMedicine. 2015 Nov 18;2(12):1862-3.

244. Vaurs C, Brun JF, Bérard E, Burcelin R, Anduze Y, Chalret du Rieu M, Hanaire H, Ritz P: A beta-cell pancreatic dysfunction participates in the hyperglycemic peaks observed after gastric bypass surgery of obese patients" Surg Obes Relat Dis. 2015 Oct 23. pii: S1550-7289(15)01008-4. doi: 10.1016/j.soard.2015.10.073. [Epub ahead of print]

245. Vaurs C, Brun JF, Bertrand M, Burcelin R, Chalret du Rieu M, Anduze Y, Hanaire H, Ritz P: Post-prandial hypoglycemia results from a non-glucose-dependent inappropriate insulin secretion in Roux-en-Y gastric bypassed patients. Metabolism. 2016 Mar;65(3):18-26. doi: 10.1016/j.metabol.2015.10.020. Epub 2015 Oct 23.

246. Brun JF, Varlet-Marie E, Raynaud de Mauverger E, Fedou C, Pollatz M. Hemorheologic effects of low intensity endurance training in type 2 diabetic patients: A pilot study. Clin Hemorheol Microcirc. 2016;61(4):579-89. 

 

247. M. Guiraudou, A.-J. Romain, M. Mawunu, K. Bedjih, C. Fédou, J.-F. Brun. Effets chroniques de l'exercice ciblé au niveau d'oxydation maximale des lipides (LIPOXmax) sur le comportement alimentaire de sujets obèses sédentaires. Science & Sports (2016) 31, 13-18 

 

248. Edelweiss Drapier, Jean-Frédéric Brun, Christine Fédou, Eric Raynaud de Mauverger : Synergie entre les effets amaigrissants de l'activité musculaire ciblée au LIPOXmax et d'un enrichissement modéré en protéines du blanc d'œuf. Science et Sports (in press) Référence: SCISPO2985 

 

249. E. Drapier, C. Fédou, E. Ghanassia, D. Nocca, J. Mercier, J.-F. Brun. L'exercice en endurance à faible intensité renforce-t-il l'efficacité amaigrissante d'une gastrectomie en manchon ? Science et Sports (in press): Référence: SCISPO2984

250 J.-F. Brun, A.J. Romain, A. Sferlazza, C. Fédou, E. Raynaud de Mauverger, J. Mercier Which individuals become fatter when they practice exercise? Science et Sports 31 (2016), pp. 214-218 

251 Varlet-Marie E, Brun JF, Raynaud de Mauverger E, Fédou C. (2016). "Exercise-induced changes in hematocrit and hematocrit/viscosity ratio in male rugby players. " Clin Hemorheol Microcirc. 2016 (in press)

252. Varlet-Marie E, Joré C, Brun JF. (2016)."Segmental bioelectrical impedance analysis (SBIA) and blood rheology: Reducing the gap between in vivo and in vitro? " Clin Hemorheol Microcirc. 2016 (in press)

253. Brun JF, Boulot P, Varlet-Marie E. (2016). "Actual vs optimal fetal hematocrit measured with punctures of cord blood in utero: Relationship with umbilical artery resistance. " Clin Hemorheol Microcirc. 2016 (in press)

254. Joré C, Brun JF, Varlet-Marie E. (2016). "Rise in RBC aggregability and concomitant decrease in blood pressure 10 days after injection of the long acting erythropoietin analogue methoxy polyethylene glycol-epoetin-? (MIRCERA®)." Clin Hemorheol Microcirc. 2016 (in press)

255. Brun JF, Varlet-Marie E, Fédou C, Raynaud de Mauverger E. (2016)."One-year follow-up of blood viscosity factors and hematocrit/viscosity ratio in elite soccer players. " Clin Hemorheol Microcirc. 2016 (in press)

256. Brun JF, Varlet-Marie E, Fédou C, Raynaud de Mauverger E. (2016)."Optimal " vs actual hematocrit in obesity and overweight. " Clin Hemorheol Microcirc. 2016 (in press)

257. Brun JF, Varlet-Marie E, Raynaud de Mauverger E. (2016)."Hematocrit and hematocrit viscosity ratio during exercise in athletes: Even closer to predicted optimal values? " ClinHemorheolMicrocirc. 2016 (in press)

258. Brun JF, Vilard O, Wojtusciszyn A, Berney T, Benhamou PY, Raynaud de Mauverger E, Fedou C, Cristol JP and Mercier J. A Simplified Assessment of Insulin Secretion without Measurement of C-Peptide Provides an Evaluation of Functional Beta-Cell Mass. Austin Diabetes Research Volume 1 Issue 2 - 2016

259. Jean-Frédéric Brun, Marlène Richou, Valentin Lasteyrie, François Bughin, Mathieu Sardinoux, David Nocca, Christine Fédou and Jacques Mercier : The Ability to Oxidize Lipids at Exercise in Surgically Weight-Reduced Obese Patients is Restored but Shifted to a Lower Exercise Intensity . Obes Diagn Treat. (2017) 1: 2.1

260. Jean-Frederic Brun, Emmanuelle Varlet-Marie, Marlène Richou, François Bughin, Eric Raynaud de Mauverger, Christine Fédou and Jacques Mercier : Balance of Substrates at Exercise in Athletes: Lipodependent vs Glucodependent Sports Sports Med Rehabil. (2017) 1: 3.1

 

See also: Papers before 2002

Tutorial articles, various communications and abstracts...

index

 

 

 



CURRICULUM VITAE